Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.48 |
| ▸ | HMGCR | P04035 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015927 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL1760681 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL1602080 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL5166822 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL9015838 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL513133 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL514166 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL1174096 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL54883 | 1.00 | — | — | |
| SCHEMBL6561950 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371995-B1 | PROCESS FOR PRODUCING PHENYLHYDROQUINONES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1993-01-20 | — | — | EP | claimed |
| CN-108558975-A | 12 beta-hydroxies-androstane-14,14- diene -16- ketone compounds and its application | 昆明理工大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-108191937-A | A kind of polyenoid androstane ketone compound and its application | 昆明理工大学 | 2018-06-22 | — | — | CN | disclosed |
| CN-105311008-B | The purposes of stearoyl amino acid or its pharmaceutical salts | 上海交通大学医学院 | 2018-03-06 | — | — | CN | disclosed |
| CN-107249589-A | Physiological activator combination block copolymer | 日本化药株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-106966960-A | A kind of phenol nitrogen-containing compound and its application | 昆明理工大学 | 2017-07-21 | — | — | CN | disclosed |
| CN-103582730-B | Oil agent for carbon fiber precursor acrylic fiber, oil agent composition for carbon fiber precursor acrylic fiber, oil agent treatment liquid for carbon fiber precursor acrylic fiber, carbon fiber precursor acrylic fiber bundle, and method for producing carbon fiber bundle using same | 三菱丽阳株式会社 | 2017-03-29 | — | — | CN | disclosed |
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120027809-A1 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2012-02-02 | — | — | US | disclosed |
| CN-100363390-C | Process for the preparation of hydroxy-vinyl-aromatic polymers or copolymers by anionic or controlled radical polymerization | CIBA SC HOLDING AG (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-1599777-A | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SC HOLDING AG (CH) | 2005-03-23 | — | — | CN | disclosed |
| EP-1471054-A1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | Sankyo Company, Limited (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040132784-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-08 | — | — | US | disclosed |
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030236297-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| CN-1128799-C | Photoactivatable nitrogen-containing bases based on alpha-amino olefins | CIBA SC HOLDING AG (CH) | 2003-11-26 | — | — | CN | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |
| CN-1251103-A | Photoactivatable nitrogen-containing bases based on alpha-amino olefins | CIBA SC HOLDING AG (CH) | 2000-04-19 | — | — | CN | disclosed |
| EP-0748823-A1 | Catalyst composition and process for the production of olefinic polymers | NIPPON OIL CO. LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-3969196-A | Process for the separation of mixtures of substances | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236297-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | PTPN7 2680/4885HMGCR 789/4885TSHR 1187/4885 |
| US-20040132784-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | PTPN7 2680/4885HMGCR 789/4885TSHR 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.