Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.46 |
| ▸ | UBE2N | P61088 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124120 | 0.85 | NISCH (0.54) | NISCHBDKRB1UBE2NLMNAPAX8 | |
| SCHEMBL1936162 | 0.80 | NISCH (0.60) | NISCHBDKRB1 | |
| SCHEMBL5125919 | 0.78 | NISCH (0.51) | NISCHUBE2NPOLBKMT2AALDH1A1 | |
| SCHEMBL6206505 | 0.76 | NISCH (0.57) | NISCHLMNARECQL | |
| SCHEMBL5110409 | 0.75 | F10 (0.39) | — | |
| SCHEMBL1935706 | 0.73 | NISCH (0.55) | NISCHBDKRB1 | |
| SCHEMBL31107315 | 0.72 | PYCR1 (0.51) | KMT2AALDH1A1 | |
| SCHEMBL3260321 | 0.72 | NISCH (0.61) | NISCHBDKRB1 | |
| SCHEMBL28546904 | 0.70 | EPHX2 (0.44) | KMT2AALDH1A1RECQL | |
| SCHEMBL5110282 | 0.70 | HTT (0.50) | POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | UGT1A1, UGT2B7, UGT1A6 | NISCH 2280/4885BDKRB1 1217/4885UBE2N 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.