Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126144 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGRM5POLB | |
| Hydrochloric Acid SCHEMBL5129387 | 0.99 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGRM5POLB | |
| SCHEMBL5131980 | 0.92 | EPHX2 (0.43) | ALDH1A1GRM5POLBPKMCCR1 | |
| SCHEMBL5128701 | 0.90 | CCR1 (0.41) | MEN1KMT2AGRM5POLBCCR1 | |
| SCHEMBL5132281 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGRM5POLB | |
| SCHEMBL5131871 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AGRM5POLB | |
| SCHEMBL5122571 | 0.86 | MEN1 (0.50) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL5128421 | 0.83 | EPHX2 (0.44) | GRM5POLB | |
| SCHEMBL5131290 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL5131291 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | ALDH1A1 2737/4885MEN1 1340/4885KMT2A 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.