Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126321 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL3859488 | 0.93 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL8318543 | 0.83 | EGFR (0.48) | ALDH1A1MAPTMEN1KMT2AHCAR3 | |
| SCHEMBL5131744 | 0.82 | AR (0.57) | ALDH1A1MAPTTSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5131746 | 0.82 | AR (0.57) | ALDH1A1MAPTTSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5118764 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL5118758 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL2849044 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ARAB9AHCAR3 | |
| SCHEMBL6570551 | 0.78 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL6671268 | 0.78 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | claimed |
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | ALDH1A1 567/4885MAPT 3258/4885MEN1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.