SCHEMBL5131744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5131746	1.00	AR (0.57)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL5120820	0.83	AR (0.50)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL5120811	0.83	AR (0.50)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL25264862	0.82	AR (0.56)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL5126331	0.82	ALDH1A1 (0.50)	CYP3A4ALDH1A1LMNACYP1A2CYP2C9
	SCHEMBL5126321	0.82	ALDH1A1 (0.50)	CYP3A4ALDH1A1LMNACYP1A2CYP2C9
	SCHEMBL8318543	0.79	EGFR (0.48)	ALDH1A1LMNAALOX15TSHRMAPK1
	SCHEMBL11313476	0.78	AR (0.75)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL11510610	0.78	AR (0.75)	ARCYP3A4CES2ABCB11ALDH1A1
	SCHEMBL11511325	0.77	AR (0.77)	ARCYP3A4CES2ABCB11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.