SCHEMBL5128345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14032746	0.93	THRA (0.48)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL5131833	0.91	RXRA (0.52)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL5122441	0.89	FFAR4 (0.52)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL5128706	0.89	RXRA (0.62)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL5057534	0.89	RXRA (0.61)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL5122986	0.88	THRA (0.51)	FFAR1FFAR4THRBPPARDPPARA
	SCHEMBL5123906	0.88	FFAR1 (0.62)	FFAR1FFAR4NR1H3THRBPPARD
	SCHEMBL5129447	0.87	FFAR4 (0.53)	FFAR1FFAR4RXRARXRBTHRB
	SCHEMBL5123879	0.86	FFAR1 (0.57)	FFAR1FFAR4RXRARXRBRXRG
	SCHEMBL14605870	0.86	FFAR4 (0.42)	FFAR1FFAR4NR1H2NR1H3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.