Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 7/20 | 0.53 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835844 | 1.00 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL32691229 | 1.00 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL10201311 | 1.00 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL2888134 | 0.86 | POLB (0.71) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL30165546 | 0.86 | POLB (0.71) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL14817758 | 0.86 | KMT2A (0.60) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL27518050 | 0.86 | KMT2A (0.60) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL3716759 | 0.86 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL10898781 | 0.85 | KDM4E (0.57) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL4713730 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GAAPOLBKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312902-B | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2022-02-18 | — | — | CN | claimed |
| CN-112312902-A | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2021-02-02 | — | — | CN | claimed |
| US-7723425-B2 | Pigment compositions with modified ATRP copolymer dispersants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | claimed |
| CN-1308627-A | 11-Aryl-benzo[b]naphtho[2,3-d]furans and 11-aryl-aryl-benzo[b]anphtho[2,3-d]thiophenes useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PROD (US) | 2001-08-15 | — | — | CN | claimed |
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | THE ROSKAMP INST (US) | 2022-03-17 | — | — | US | disclosed |
| CN-112312902-B | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-113668004-A | Method for electrochemically synthesizing non-natural amino acid derivatives | 浙江工业大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |
| US-10995084-B2 | Pyrrolidine derivative | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-04 | — | — | US | disclosed |
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112312902-A | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2021-02-02 | — | — | CN | disclosed |
| EP-1129076-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AS LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000029380-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AS LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 2000-05-25 | — | — | WO | disclosed |
| EP-0473637-B1 | PEROXYACID MANUFACTURE | SOLVAY INTEROX LTD (GB) | 1995-03-22 | — | — | EP | disclosed |
| US-5326904-A | For low temperature detergents | SOLVAY INTEROX LIMITED (GB) | 1994-07-05 | — | — | US | disclosed |
| US-5220052-A | Controlling the rate of addition of a solution of carboxylic acid in concentrated sulfuric acid to Caro's solution having a particular range of components, i.e. hydrogen peroxide, water and sulfuric acid | INTEROX CHEMICALS LIMITED (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0473637-A1 | PEROXYACID MANUFACTURE. | INTEROX CHEMICALS LTD (GB) | 1992-03-11 | — | — | EP | disclosed |
| US-5010204-A | Glaucoma treatment | INSTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) | 1991-04-23 | — | — | US | disclosed |
| WO-1990014336-A1 | PEROXYACID MANUFACTURE | INTEROX CHEMICALS LIMITED (GB) | 1990-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995084-B2 | Pyrrolidine derivative | CALCRL, NPY1R, GRPR | ALDH1A1 2551/4885GAA 3678/4885POLB 2693/4885 |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | NFKBIA, NFRKB, IKBKG | ALDH1A1 4214/4885GAA 828/4885POLB 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.