Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.46 |
| ▸ | CTSA | P10619 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126507 | 0.95 | RXRA (0.53) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL5132497 | 0.91 | THRA (0.52) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL4435008 | 0.89 | THRA (0.55) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL5122986 | 0.88 | THRA (0.51) | THRATHRBSLC13A5CTSAFFAR1 | |
| SCHEMBL5123953 | 0.88 | RXRA (0.60) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL5128706 | 0.87 | RXRA (0.62) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL5129224 | 0.86 | FFAR4 (0.50) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL5128966 | 0.86 | FFAR1 (0.56) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL4437946 | 0.86 | THRA (0.58) | THRATHRBSLC13A5CTSAFFAR1 | |
| SCHEMBL5123157 | 0.85 | THRA (0.50) | THRATHRBSLC13A5CTSAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PPARG, PPARA, PPARD | THRA 228/4885THRB 130/4885RXRA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.