SCHEMBL5129233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5124542	0.89	ADRA1B (0.63)	ADRA1BIDO1TOP2ABACE1BACE2
	SCHEMBL5116595	0.87	IDO1 (0.45)	IDO1POLBTP53MAPTALDH1A1
	SCHEMBL5118408	0.82	ADRA1B (0.47)	ADRA1BIDO1TOP2APOLBTP53
	SCHEMBL998603	0.81	ADRA1B (0.73)	ADRA1BIDO1TOP2APOLBTP53
	SCHEMBL5122346	0.81	PTGS2 (0.53)	ADRA1BTP53MAPTALDH1A1GAA
	SCHEMBL5120431	0.79	ADRA1B (0.47)	ADRA1BIDO1POLBTP53MAPT
	SCHEMBL5122743	0.78	BRD4 (0.55)	ADRA1BTOP2APOLBTP53MAPT
	SCHEMBL5121648	0.78	ADRA1B (0.45)	ADRA1BIDO1TOP2APOLBTP53
	SCHEMBL5114935	0.77	ADRA1B (0.45)	ADRA1BIDO1TOP2AALDH1A1GAA
	SCHEMBL997742	0.77	GAA (0.59)	ADRA1BIDO1TOP2APOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.