SCHEMBL512968

SCHEMBL512968

CCCCN(CCCC)c1ccc2c(c1)Oc1ccc(Nc3ccccc3Cl)cc1C21OC(=O)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
FTO Q9C0B1 7/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
SMAD3 P84022 1/20 0.41
PRMT1 Q99873 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TTR P02766 1/20 0.36
GSTP1 P09211 1/20 0.35
PGR P06401 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30192749 1.00 CYP3A4 (0.44) CYP3A4FTOMAPTMEN1HTT
SCHEMBL30043282 1.00 CYP3A4 (0.44) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6409588 0.92 CYP3A4 (0.44) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6405302 0.91 CYP3A4 (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL30473085 0.91 CYP3A4 (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL30010023 0.87 CYP3A4 (0.45) CYP3A4FTOMAPTMEN1HTT
SCHEMBL21440430 0.84 CYP3A4 (0.57) CYP3A4FTOMAPTMEN1HTT
SCHEMBL275322 0.83 CYP3A4 (0.56) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6404218 0.83 CYP3A4 (0.49) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6403996 0.83 CYP3A4 (0.49) CYP3A4FTOMAPTMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8593633-B2 Cure degree evaluation method, cure degree evaluation sheet, and cure degree evaluation system for evaluating cure degree of active energy ray-curable resin composition OMRON CORPORATION (JP) 2013-11-26 US claimed
US-20120026501-A1 CURE DEGREE EVALUATION METHOD, CURE DEGREE EVALUATION SHEET, AND CURE DEGREE EVALUATION SYSTEM FOR EVALUATING CURE DEGREE OF ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION OMRON CORPORATION (JP) 2012-02-02 US claimed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
WO-2023105508-A1 COMPOSITION FOR WET INDICATOR AND WET INDICATOR HENKEL AG & CO. KGAA (DE) 2023-06-15 WO disclosed
US-11655387-B2 Thermochromic pigment compositions SOCIéTé BIC (FR) 2023-05-23 US disclosed
US-11543750-B2 Lithographic printing plate precursor and method for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
WO-2022255254-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT AND TOY USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION 三菱ケミカル株式会社 2022-12-08 WO disclosed
US-20100134865-A1 Electrochromic Display Device FUNAI ELECTRIC ADVANCED APPLIED TECHNOLOGY RESEARCH INSTITUTE INC. (JP) 2010-06-03 US disclosed
US-20100134865-A1 Electrochromic Display Device FUNAI ELECTRIC ADVANCED APPLIED TECHNOLOGY RESEARCH INSTITUTE INC. (JP) 2010-06-03 US disclosed
EP-2187256-A2 Electrochromic display device using a leuco dye and a passive matrix Funai Electric Co., Ltd. (JP) 2010-05-19 EP disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-6953645-B2 Preparation of nanocapsule compositions and their toner composition for thermosensitive rewritable recording media KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2005-10-11 US disclosed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP disclosed
US-20030215729-A1 Preparation of nanocapsule compositions and their toner composition for thermosensitive rewritable recording media KOREA RESEARCH INSTITUDE OF CHEMICAL TECHNOLOGY 2003-11-20 US disclosed
US-5500040-A Ultraviolet-curable thermochromic ink composition SAKURA COLOR PRODUCTS CORPORATION (JP) 1996-03-19 US disclosed
EP-0480162-A1 Dyeing method and dyed product MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1992-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 CYP3A4 2565/4885FTO 179/4885MAPT 333/4885
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG CYP3A4 1695/4885FTO 161/4885MAPT 3053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.