Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130347 | 1.00 | HPGD (0.40) | HPGDTXNRD1MIFALDH1A1MEN1 | |
| SCHEMBL5972133 | 0.85 | TXNRD1 (0.42) | HPGDTXNRD1MIFALDH1A1MEN1 | |
| SCHEMBL5123860 | 0.82 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5123863 | 0.82 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5126008 | 0.80 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL5126018 | 0.80 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL5122458 | 0.78 | ENPP2 (0.48) | HPGDTXNRD1ALDH1A1MEN1KMT2A | |
| SCHEMBL5126001 | 0.75 | MAPT (0.39) | TXNRD1ALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5120760 | 0.75 | MAPT (0.39) | HPGDALDH1A1MAPTPOLBHTT | |
| SCHEMBL5120767 | 0.75 | MAPT (0.39) | HPGDALDH1A1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685090-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2006-08-02 | — | — | EP | claimed |
| WO-2005042464-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2005-05-12 | — | — | WO | claimed |
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | HPGD 326/4885TXNRD1 562/4885MIF 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.