Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.71 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143812 | 0.85 | HPGD (0.78) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL1058712 | 0.85 | HPGD (0.78) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL312255 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL6700893 | 0.83 | AKR1C3 (0.71) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL17786454 | 0.83 | NPC1 (0.71) | AKR1C3AKR1C2AKR1C1KMT2AHPGD | |
| SCHEMBL17786570 | 0.82 | EGFR (0.58) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL17786446 | 0.80 | AR (0.74) | MEN1KMT2AHPGDTP53ALOX15 | |
| 6-Aminoflavone SCHEMBL926716 | 0.79 | EGFR (0.82) | HPGDTP53ALOX15SMN1; SMN2EGFR | |
| 6-Aminoflavone SCHEMBL31550004 | 0.79 | EGFR (0.82) | HPGDTP53ALOX15SMN1; SMN2EGFR | |
| SCHEMBL5126242 | 0.77 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1C1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863323-B1 | Flavonols | THE UNIVERSITY OF MELBOURNE (AU) | 2011-01-04 | — | — | US | disclosed |