6-Aminoflavone

6-Aminoflavone

SCHEMBL31550004

Nc1ccc2oc(-c3ccccc3)cc(=O)c2c1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.82
SRC P12931 1/20 0.82
PLA2G2A P14555 3/20 0.73
PLA2G4A P47712 3/20 0.73
TNKS O95271 3/20 0.68
TP53 P04637 3/20 0.68
HPGD P15428 3/20 0.68
MAPT P10636 3/20 0.68
GABRP O00591 2/20 0.68
GABRD O14764 2/20 0.68
NPC1 O15118 2/20 0.68
CYP3A4 P08684 2/20 0.68
ADORA3 P0DMS8 2/20 0.68
GABRA1 P14867 2/20 0.68
GABRB1 P18505 2/20 0.68
GABRG2 P18507 2/20 0.68
GABRB3 P28472 2/20 0.68
GABRA5 P31644 2/20 0.68
GABRA3 P34903 2/20 0.68
GABRA2 P47869 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Aminoflavone SCHEMBL926716 1.00 EGFR (0.82) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL17786600 0.97 EGFR (0.82) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL17786489 0.87 EGFR (0.72) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL17786474 0.87 EGFR (0.72) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL1143392 0.87 CYP19A1 (0.68) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL925553 0.84 EGFR (0.82) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL17786560 0.84 GABRP (0.79) EGFRSRCTNKSTP53HPGD
SCHEMBL7207188 0.84 CYP3A4 (0.79) EGFRSRCTNKSTP53HPGD
SCHEMBL24227286 0.83 PLA2G2A (0.97) EGFRSRCPLA2G2APLA2G4ATNKS
SCHEMBL29711102 0.82 PLA2G2A (0.81) EGFRSRCPLA2G2APLA2G4ATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119770481-B NR4A1 transcriptional activity inhibitor and application thereof 浙江省肿瘤医院 2025-06-13 CN claimed
CN-119770481-A NR4A1 transcriptional activity inhibitor and application thereof 浙江省肿瘤医院 2025-04-08 CN claimed
CN-119770481-B NR4A1 transcriptional activity inhibitor and application thereof 浙江省肿瘤医院 2025-06-13 CN disclosed
CN-119770481-A NR4A1 transcriptional activity inhibitor and application thereof 浙江省肿瘤医院 2025-04-08 CN disclosed