Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513990 | 0.92 | XIAP (0.33) | FABP4 | |
| SCHEMBL514077 | 0.86 | AKT1 (0.39) | FABP4 | |
| SCHEMBL514254 | 0.86 | AKT1 (0.39) | FABP4 | |
| SCHEMBL514234 | 0.84 | CDC7 (0.31) | CDC7DBF4 | |
| SCHEMBL513508 | 0.84 | XIAP (0.36) | FABP4 | |
| SCHEMBL14876807 | 0.84 | FABP4 (0.34) | FABP4CDC7DBF4 | |
| SCHEMBL14876808 | 0.84 | FABP4 (0.34) | FABP4CDC7DBF4 | |
| SCHEMBL12289039 | 0.81 | FABP4 (0.36) | FABP4CDC7DBF4 | |
| SCHEMBL514802 | 0.80 | PTGDR2 (0.35) | — | |
| SCHEMBL513693 | 0.79 | SYK (0.32) | FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028918-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF MAKING SAME | GLAXO WELLCOME MANUFACTURING PTE LTD. (SG) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028918-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF MAKING SAME | PIK3CA, G6PC1, PIK3C2B | FABP4 4044/4885CDC7 1331/4885DBF4 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.