Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923168 | 0.98 | NOS1 (0.43) | NOS1TLR8TLR7DAOFDPS | |
| SCHEMBL854767 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL2247867 | 0.89 | NOS1 (0.40) | NOS1TLR8TLR7DAOFDPS | |
| Hydrochloric Acid SCHEMBL3510077 | 0.89 | NOS1 (0.40) | NOS1TLR8TLR7DAOFDPS | |
| SCHEMBL7100687 | 0.87 | DAO (0.43) | TLR8TLR7DAOFDPSTSHR | |
| SCHEMBL14995729 | 0.83 | DAO (0.37) | TLR8TLR7DAOFDPSTSHR | |
| SCHEMBL1026265 | 0.82 | — | — | |
| Methylamine SCHEMBL27939089 | 0.82 | TLR8 (0.48) | NOS1TLR8TLR7 | |
| SCHEMBL11440961 | 0.81 | TBXAS1 (0.47) | NOS1TLR8TLR7DAOLMNA | |
| SCHEMBL6114640 | 0.81 | TBXAS1 (0.47) | NOS1TLR8TLR7DAOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235628-B1 | 1-ARYLPYRAZOLES | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| EP-0269839-A1 | 5-Acylamino-pyrazole derivatives | BAYER AG (DE) | 1988-06-08 | — | — | EP | claimed |
| EP-0242573-A1 | 5-Acylamino-pyrazole derivatives | BAYER AG (DE) | 1987-10-28 | — | — | EP | claimed |
| EP-0235628-A2 | 1-Arylpyrazoles | BAYER AG (DE) | 1987-09-09 | — | — | EP | claimed |
| EP-0233341-A1 | 5-Heterocyclyl-1-aryl-pyrazole | BAYER AG (DE) | 1987-08-26 | — | — | EP | claimed |
| EP-0231510-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1987-08-12 | — | — | EP | claimed |
| US-20080045524-A1 | Selective NPY (Y5) antagonists | H. LUNDBECK A/S (DK) | 2008-02-21 | — | — | US | disclosed |
| US-20080045524-A1 | Selective NPY (Y5) antagonists | H. LUNDBECK A/S (DK) | 2008-02-21 | — | — | US | disclosed |
| US-20080045524-A1 | Selective NPY (Y5) antagonists | H. LUNDBECK A/S (DK) | 2008-02-21 | — | — | US | disclosed |
| EP-1816127-A1 | TRIAZINE DERIVATIVES FOR USE AS SELECTIVE NPY (Y5) ANTAGONISTS | H. Lundbeck A/S (DK) | 2007-08-08 | — | — | EP | disclosed |
| EP-1816127-A1 | TRIAZINE DERIVATIVES FOR USE AS SELECTIVE NPY (Y5) ANTAGONISTS | H. Lundbeck A/S (DK) | 2007-08-08 | — | — | EP | disclosed |
| US-7189720-B2 | Selective NPY (Y5) antagonists | H. LUNDBECK A/S (DK) | 2007-03-13 | — | — | US | disclosed |
| US-7189720-B2 | Selective NPY (Y5) antagonists | H. LUNDBECK A/S (DK) | 2007-03-13 | — | — | US | disclosed |
| EP-0231510-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1987-08-12 | — | — | EP | disclosed |
| EP-0226156-A2 | 1-Aryl-pyrazoles | BAYER AG (DE) | 1987-06-24 | — | — | EP | disclosed |
| EP-0216102-A1 | 1-Arylpyrazoles | BAYER AG (DE) | 1987-04-01 | — | — | EP | disclosed |
| EP-0212354-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0212353-A2 | 1-Aryl-5-hydrazino-pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0207285-A1 | 5-Amino-1-pyridyl-pyrazoles | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0205022-A2 | 1-Aryl-5-alkoximinoalkyl amino pyrazoles | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045524-A1 | Selective NPY (Y5) antagonists | NPY5R, NPY1R, NPY2R | NOS1 4238/4885TLR8 1274/4885TLR7 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.