Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125427 | 0.98 | CYP46A1 (0.42) | CYP46A1BDKRB1AVPR1ARAB9A | |
| SCHEMBL5132192 | 0.94 | EPHX2 (0.40) | CYP46A1FKBP1AAVPR1A | |
| SCHEMBL3824549 | 0.92 | FKBP1A (0.41) | CYP46A1BDKRB1FKBP1AAVPR1ANPC1 | |
| SCHEMBL3406117 | 0.91 | BDKRB1 (0.44) | BDKRB1FKBP1A | |
| SCHEMBL5131956 | 0.89 | FKBP1A (0.47) | CYP46A1FKBP1ANPC1RAB9A | |
| SCHEMBL5127947 | 0.89 | BDKRB1 (0.42) | BDKRB1NPC1RAB9A | |
| SCHEMBL3412504 | 0.88 | BDKRB1 (0.43) | BDKRB1FKBP1A | |
| SCHEMBL3408443 | 0.88 | BDKRB1 (0.43) | BDKRB1FKBP1A | |
| SCHEMBL5132117 | 0.87 | CYP46A1 (0.44) | CYP46A1FKBP1ANPC1RAB9A | |
| SCHEMBL14411693 | 0.86 | BDKRB1 (0.43) | BDKRB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | CYP46A1 3216/4885BDKRB1 1/4885FKBP1A 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.