Sugi Predict

Sugi Predict / Compounds / Benzidine

Benzidine

Benzidine

SCHEMBL5132264

Nc1ccc(-c2ccc(N)cc2)cc1.c1nnn[nH]1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.48
▸ CYP3A4 P08684 4/20 0.48
▸ TP53 P04637 4/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ HSD17B10 Q99714 5/20 0.41
▸ TAAR1 Q96RJ0 2/20 0.41
▸ ASIC3 Q9UHC3 1/20 0.39
▸ NPC1 O15118 5/20 0.39
▸ RAB9A P51151 5/20 0.39
▸ MAPT P10636 5/20 0.39
▸ KDM4E B2RXH2 4/20 0.39
▸ HPGD P15428 4/20 0.39
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ KIF11 P52732 1/20 0.35
▸ METAP2 P50579 1/20 0.35
▸ CYP17A1 P05093 1/20 0.35
▸ CYP19A1 P11511 1/20 0.35
▸ CYP11B1 P15538 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL7639491 0.98 ALDH1A1 (0.46) ALDH1A1CYP3A4TP53TDP1HSD17B10
Biphenyl-4-Amine SCHEMBL28165279 0.92 HSD17B10 (0.56) ALDH1A1CYP3A4TP53TDP1HSD17B10
Benzidine SCHEMBL9632331 0.91 ALDH1A1 (0.39) ALDH1A1CYP3A4TP53TDP1HSD17B10
Aniline SCHEMBL15405423 0.83 TSHR (0.48) ALDH1A1CYP3A4TDP1HSD17B10TAAR1
Tetrazole SCHEMBL27988029 0.81 ASIC3 (0.31) ALDH1A1CYP3A4TP53TDP1ASIC3
Tetrazole SCHEMBL7635201 0.80 RAD52 (0.47) ALDH1A1CYP3A4TP53HSD17B10NPC1
Tetrazole SCHEMBL9630986 0.79 MEN1 (0.38) ALDH1A1CYP3A4TP53TDP1HSD17B10
Biphenyl SCHEMBL9308 0.77 ALDH1A1 (0.43) ALDH1A1CYP3A4TDP1HSD17B10TAAR1
Biphenyl SCHEMBL28349299 0.77 AKT2 (0.38) ALDH1A1CYP3A4TDP1HSD17B10TAAR1
Tetrazole SCHEMBL29023855 0.76 ALDH1A1 (0.41) ALDH1A1CYP3A4TAAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134057-A METHOD OF PROVIDING A SUBSTRATE WITH A LAYER COMPRISING A POLYVINYL BASED HYDROGEL AND A BIOCHEMICALLY ACTIVE MATERIAL 501 PPG BIOMEDICAL SYSTEMS, INC. (US) 1992-07-28 — — US claimed
EP-0363504-A1 Method of providing a substrate with a layer comprising a polyvinylbased hydrogel and a biochemically active material Dräger Nederland B.V. (NL) 1990-04-18 — — EP claimed
US-8361768-B2 Heat resistant bioactive composition REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-01-29 — — US disclosed
US-20120252090-A1 HEAT RESISTANT BIOACTIVE COMPOSITION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2012-10-04 — — US disclosed
US-8222015-B2 Heat resistant bioactive composition TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2012-07-17 — — US disclosed
US-20080293117-A1 HEAT RESISTANT BIOACTIVE COMPOSITION TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2008-11-27 — — US disclosed
WO-2008141263-A1 HEAT RESISTANT BIOACTIVE COMPOSITION TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2008-11-20 — — WO disclosed
US-5134057-A METHOD OF PROVIDING A SUBSTRATE WITH A LAYER COMPRISING A POLYVINYL BASED HYDROGEL AND A BIOCHEMICALLY ACTIVE MATERIAL 501 PPG BIOMEDICAL SYSTEMS, INC. (US) 1992-07-28 — — US disclosed
EP-0363504-A1 Method of providing a substrate with a layer comprising a polyvinylbased hydrogel and a biochemically active material Dräger Nederland B.V. (NL) 1990-04-18 — — EP disclosed