Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 16/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127947 | 0.92 | BDKRB1 (0.42) | BDKRB1ALDH1A1 | |
| SCHEMBL3809047 | 0.91 | ALDH1A1 (0.47) | BDKRB1ALDH1A1CASP3CASP7CYP2D6 | |
| SCHEMBL5128645 | 0.91 | MEN1 (0.43) | BDKRB1ALDH1A1TSHR | |
| SCHEMBL5132121 | 0.91 | BDKRB1 (0.41) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL5128006 | 0.90 | ALDH1A1 (0.46) | BDKRB1ALDH1A1CASP3CASP7CYP3A4 | |
| SCHEMBL14411693 | 0.90 | BDKRB1 (0.43) | BDKRB1ALDH1A1 | |
| SCHEMBL5123809 | 0.90 | BDKRB1 (0.43) | BDKRB1ALDH1A1 | |
| SCHEMBL3818678 | 0.88 | ALDH1A1 (0.47) | BDKRB1ALDH1A1CASP3CASP7CYP2D6 | |
| SCHEMBL14411784 | 0.88 | MEN1 (0.44) | BDKRB1ALDH1A1TSHR | |
| SCHEMBL5131948 | 0.88 | BDKRB1 (0.42) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | BDKRB1 1/4885ALDH1A1 2737/4885CASP3 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.