SCHEMBL5133065

SCHEMBL5133065

C=CCC(CC=C)CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
CACNA2D1 P54289 2/20 0.30
CACNB3 P54284 1/20 0.30
CACNA1C Q13936 1/20 0.30
PGR P06401 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR2B P41595 1/20 0.30
CACNA2D2 Q9NY47 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1883109 0.85 TSHR (0.36) TSHRCACNA2D1CACNB3CACNA1CPGR
SCHEMBL22783301 0.78
SCHEMBL22253952 0.78
SCHEMBL20889048 0.78 CACNA2D1 (0.34) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL180719 0.77
SCHEMBL9445609 0.76 LMNA (0.42) TSHRALDH1A1
SCHEMBL73307 0.75
Ethylene SCHEMBL28834218 0.74 ALDH1A1 (0.30) TSHRALDH1A1MAPK1
SCHEMBL19428112 0.74 TSHR (0.40) TSHRALDH1A1CYP3A4
SCHEMBL21208 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008009680-A1 NOVEL HYDROGEN-RICH 1,3-DIALKOXYDISILOXANES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) 2008-01-24 WO disclosed