Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.72 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525973 | 0.84 | KIF11 (0.74) | KIF11ERAP1PFKFB3PTGES2 | |
| SCHEMBL4662603 | 0.84 | KIF11 (1.00) | KIF11ERAP1PFKFB3NTRK1FLT3 | |
| SCHEMBL5133295 | 0.82 | KIF11 (0.72) | KIF11ERAP1PFKFB3MGLLPTPN1 | |
| SCHEMBL12416812 | 0.81 | CDK1 (0.59) | — | |
| SCHEMBL14009915 | 0.81 | MGLL (0.56) | KIF11PFKFB3MGLLPTPN1KDM1A | |
| SCHEMBL27826397 | 0.77 | CA1 (0.66) | KIF11 | |
| SCHEMBL4399152 | 0.75 | KIF11 (0.54) | KIF11ERAP1PFKFB3PTPN1ACLY | |
| SCHEMBL5425703 | 0.75 | KIF11 (0.74) | KIF11MGLL | |
| SCHEMBL16676705 | 0.74 | KIF11 (0.67) | KIF11ERAP1PFKFB3MGLL | |
| SCHEMBL4441545 | 0.73 | KIF11 (0.49) | KIF11ERAP1MGLLPTPN1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940767-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007030567-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |