Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.46 |
| ▸ | PGR | P06401 | 6/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395537 | 0.94 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL2395839 | 0.86 | MAPT (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL2390304 | 0.82 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL2397954 | 0.82 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL2390300 | 0.82 | NR3C1 (0.50) | NR3C1PGRNR3C2AR | |
| SCHEMBL2391865 | 0.81 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL2393569 | 0.80 | PGR (0.45) | NR3C1PGRNR3C2ARESR1 | |
| SCHEMBL2394060 | 0.80 | NR3C1 (0.53) | NR3C1PGRNR3C2AR | |
| SCHEMBL2393214 | 0.78 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL2396013 | 0.77 | NR3C1 (0.49) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1944290-A1 | NOVEL 1-2-DIHYDROQUINOLINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |