Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458974 | 0.78 | — | — | |
| SCHEMBL9849643 | 0.76 | — | — | |
| SCHEMBL4694810 | 0.76 | — | — | |
| SCHEMBL486744 | 0.70 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL28026340 | 0.70 | — | — | |
| SCHEMBL1592496 | 0.69 | — | — | |
| SCHEMBL6410731 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL29024517 | 0.67 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL996242 | 0.67 | MAPK1 (0.32) | MAPK1 | |
| Hydrochloric Acid SCHEMBL29024671 | 0.67 | MAPK1 (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999131-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007099171-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-09-07 | — | — | WO | disclosed |