Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.40 |
| ▸ | GABRP | O00591 | 7/20 | 0.36 |
| ▸ | GABRD | O14764 | 7/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.36 |
| ▸ | GABRE | P78334 | 7/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707012 | 0.85 | TMEM97 (0.38) | TMEM97GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL921624 | 0.80 | CNR2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL706131 | 0.79 | TACR1 (0.36) | TMEM97GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5133971 | 0.76 | TMEM97 (0.43) | TMEM97GRIN1GRIN2B | |
| SCHEMBL707536 | 0.74 | KCNH2 (0.54) | — | |
| SCHEMBL3856816 | 0.74 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL4304295 | 0.74 | KCNH2 (0.54) | — | |
| SCHEMBL3861861 | 0.72 | KCNH2 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3861849 | 0.72 | KCNH2 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL706987 | 0.72 | KCNH2 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893599-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134378-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | disclosed |