Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141328 | 0.85 | P2RY12 (0.55) | ALDH1A1P2RY12 | |
| SCHEMBL5066024 | 0.76 | ALDH1A1 (0.83) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL3586010 | 0.75 | ALDH1A1 (0.71) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL30999841 | 0.75 | ALDH1A1 (0.78) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL23120427 | 0.74 | KDM4E (0.64) | ALDH1A1P2RY12KDM4EMAPTNPSR1 | |
| SCHEMBL3926740 | 0.74 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL30999844 | 0.74 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL3599232 | 0.74 | ALDH1A1 (0.74) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL30918308 | 0.73 | KDM4E (0.63) | ALDH1A1P2RY12KDM4EMAPTNPSR1 | |
| SCHEMBL3589122 | 0.73 | KDM4E (0.63) | ALDH1A1P2RY12KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904474-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007008140-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |