Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774854 | 0.86 | CNR1 (0.42) | SOAT1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL4822553 | 0.80 | HDAC3 (0.37) | SOAT1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL7974672 | 0.79 | LMNA (0.37) | SOAT1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL1289911 | 0.78 | — | — | |
| SCHEMBL1043398 | 0.78 | — | — | |
| SCHEMBL14813859 | 0.78 | — | — | |
| SCHEMBL8002641 | 0.76 | — | — | |
| SCHEMBL4865819 | 0.76 | — | — | |
| SCHEMBL17152223 | 0.76 | — | — | |
| SCHEMBL701233 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442779-B2 | Isolation of proteins | UPFRONT CHROMATOGRAPHY A/S (DK) | 2008-10-28 | — | — | US | disclosed |
| US-20050176122-A1 | Isolation of proteins | UPFRONT CHROMATOGRAPHY A/S | 2005-08-11 | — | — | US | disclosed |