Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775001 | 0.88 | FAAH (0.46) | LMNASOAT1MEN1FAAHTP53 | |
| SCHEMBL6008933 | 0.82 | MCL1 (0.34) | LMNAMCL1 | |
| SCHEMBL4822553 | 0.80 | HDAC3 (0.37) | LMNASOAT1MEN1FAAHTP53 | |
| SCHEMBL5133636 | 0.79 | SOAT1 (0.37) | LMNASOAT1MEN1FAAHTP53 | |
| SCHEMBL8654432 | 0.75 | — | — | |
| SCHEMBL7021101 | 0.74 | TSHR (0.37) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL1297846 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3355086 | 0.72 | LMNA (0.48) | LMNASOAT1MEN1FAAHTP53 | |
| SCHEMBL8002641 | 0.72 | — | — | |
| SCHEMBL487785 | 0.72 | LMNA (0.48) | LMNASOAT1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001057040-A1 | 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-08-09 | — | — | WO | disclosed |