Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522490 | 0.71 | GAA (0.35) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| Bicarbonate SCHEMBL513277 | 0.69 | CDK8 (0.37) | CDK8ACVR1ALDH1A1GAAKDM4E | |
| SCHEMBL1889853 | 0.66 | L3MBTL1 (0.43) | CDK8ACVR1ALDH1A1GAAKDM4E | |
| SCHEMBL15768037 | 0.66 | KDM4E (0.39) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| SCHEMBL12647732 | 0.62 | KDM4E (0.42) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| SCHEMBL8854253 | 0.62 | L3MBTL1 (0.38) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| SCHEMBL387508 | 0.62 | ERCC1 (0.37) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| SCHEMBL14844458 | 0.62 | KDM4E (0.39) | CDK8ACVR1ALDH1A1GAAKDM4E | |
| SCHEMBL9194890 | 0.62 | KDM4E (0.42) | ALDH1A1GAAKDM4EL3MBTL1MAPT | |
| SCHEMBL8588935 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | CDK8 3755/4885ACVR1 1220/4885ALDH1A1 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.