Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652340 | 0.82 | NAAA (0.58) | NAAAL3MBTL1MLYCDALDH1A1MEN1 | |
| SCHEMBL1857574 | 0.81 | NAAA (0.57) | NAAAL3MBTL1MLYCDALDH1A1MEN1 | |
| SCHEMBL1853750 | 0.79 | NPC1 (0.62) | NAAAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1853512 | 0.78 | NAAA (0.64) | NAAAL3MBTL1MLYCDSIGMAR1TMEM97 | |
| SCHEMBL1856912 | 0.78 | TMEM97 (0.60) | NAAAL3MBTL1MLYCDSIGMAR1TMEM97 | |
| SCHEMBL1859658 | 0.78 | NAAA (0.64) | NAAAL3MBTL1MLYCDSIGMAR1TMEM97 | |
| SCHEMBL1851125 | 0.78 | NAAA (0.64) | NAAAL3MBTL1MLYCDSIGMAR1TMEM97 | |
| SCHEMBL1852914 | 0.77 | NAAA (0.56) | NAAAL3MBTL1MLYCDSIGMAR1TMEM97 | |
| SCHEMBL1857690 | 0.77 | NAAA (0.56) | NAAAL3MBTL1MLYCDALDH1A1MEN1 | |
| SCHEMBL1852987 | 0.77 | TMEM97 (0.56) | NAAAL3MBTL1MLYCDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |