Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856912 | 0.84 | TMEM97 (0.60) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1859658 | 0.84 | NAAA (0.64) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1857574 | 0.84 | NAAA (0.57) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1853512 | 0.84 | NAAA (0.64) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1851125 | 0.84 | NAAA (0.64) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1852914 | 0.83 | NAAA (0.56) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1857690 | 0.83 | NAAA (0.56) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1857734 | 0.82 | NAAA (0.61) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL5133773 | 0.82 | NAAA (0.51) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1853672 | 0.82 | TMEM97 (0.52) | NAAAL3MBTL1MLYCDTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185118-A1 | Use of methylene amide derivatives in cardiovascular disorders | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185118-A1 | Use of methylene amide derivatives in cardiovascular disorders | TNNI3, TNNT2, ADM2 | NAAA 684/4885L3MBTL1 2368/4885MLYCD 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.