Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497571 | 0.83 | NCEH1 (0.55) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30423720 | 0.78 | NCEH1 (0.50) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29054179 | 0.78 | NCEH1 (0.50) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL14149856 | 0.78 | NCEH1 (0.50) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL1036677 | 0.76 | HPGD (0.46) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1036678 | 0.76 | HPGD (0.46) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL71131 | 0.74 | NCEH1 (0.59) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL1638703 | 0.74 | CA12 (0.60) | NCEH1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1648076 | 0.74 | NCEH1 (0.59) | NCEH1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29404644 | 0.74 | NCEH1 (0.59) | NCEH1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973888-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079162-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-12 | — | — | WO | disclosed |