SCHEMBL1638703

SCHEMBL1638703

COC(=O)c1c(O)ccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA14 Q9ULX7 1/20 0.60
NCEH1 Q6PIU2 1/20 0.59
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPT P10636 1/20 0.56
ABCG2 Q9UNQ0 4/20 0.52
KDM4E B2RXH2 2/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 2/20 0.47
TSHR P16473 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.47
RCE1 Q9Y256 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13176746 0.88 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL10880498 0.85 ABCG2 (0.53) MEN1KMT2AMAPTABCG2KDM4E
SCHEMBL8599970 0.83 ABCG2 (0.50) CA12CA1CA2CA7CA9
SCHEMBL9297361 0.82 ABCG2 (0.50) NCEH1MEN1KMT2AMAPTABCG2
SCHEMBL71131 0.82 NCEH1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL1648076 0.82 NCEH1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL29404644 0.82 NCEH1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9193765 0.81 NCEH1 (0.48) NCEH1MEN1KMT2AMAPTABCG2
SCHEMBL28517298 0.81 ABCG2 (0.49) NCEH1MEN1KMT2AMAPTABCG2
SCHEMBL2217827 0.81 ABCG2 (0.47) NCEH1MEN1KMT2AMAPTABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559504-B2 Benzotriazole derivative UBE CORPORATION (JP) 2026-02-24 US disclosed
EP-3978073-B1 1H-BENZO[D][1,2,3]TRIAZOLE DERIVATIVES AS KEAP1 INHIBITORS FOR THE TREATMENT OF RENAL DISEASES UBE CORP (JP) 2025-10-15 EP disclosed
CN-114174289-B Benzotriazole derivatives UBE株式会社 2025-03-07 CN disclosed
US-12011432-B2 Method of modulating ribonucleotide reductase CASE WESTERN RESERVE UNIVERSITY (US) 2024-06-18 US disclosed
CN-117651750-A Ultraviolet absorber, method for producing same, composition, molded article, and coating film 东洋油墨SC控股株式会社 2024-03-05 CN disclosed
WO-2023242454-A1 HYBRID MATERIAL FOR DETECTING ACID AND BASE VAPOURS UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2023-12-21 WO disclosed
CN-117083263-A Hydrazide compound, curable resin composition, sealant for liquid crystal display element, and liquid crystal display element 积水化学工业株式会社 2023-11-17 CN disclosed
CN-114846085-B Resin composition and molded article 东洋油墨SC控股株式会社 2023-09-08 CN disclosed
WO-2023286725-A1 UV ABSORBER AND MANUFACTURING METHOD THEREOF, COMPOSITION, MOLDED BODY AND COATING FILM 東洋インキSCホールディングス株式会社 2023-01-19 WO disclosed
WO-2022270467-A1 HYDRAZIDE COMPOUND, CURABLE RESIN COMPOSITION, SEALING AGENT FOR LIQUID CRYSTAL DISPLAY ELEMENTS, AND LIQUID CRYSTAL DISPLAY ELEMENT 積水化学工業株式会社 2022-12-29 WO disclosed
US-5270730-A Jet recording method and apparatus for discharging normally solid recording material by causing generated bubble to communicate with ambience CANON KABUSHIKI KAISHA (JP) 1993-12-14 US disclosed
EP-0256456-B1 PIGMENT COMPOSITION DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1993-03-10 EP disclosed
EP-0256454-B1 PIGMENT COMPOSITION DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1993-03-03 EP disclosed
EP-0479501-A2 Jet recording method, normally solid recording material and recording apparatus for the method CANON KABUSHIKI KAISHA (JP) 1992-04-08 EP disclosed
US-4767465-A POLYESTER DISPERSANT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1988-08-30 US disclosed
US-4762568-A PHOSPHORIC ESTER OF A POLYESTER AS DISPERSANT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1988-08-09 US disclosed
EP-0256456-A2 Pigment composition DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1988-02-24 EP disclosed
EP-0256454-A2 Pigment composition DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1988-02-24 EP disclosed
US-4515849-A Transfer printing sheet, printing method and printed article MATSUI SHIKISO CHEMICAL CO. LTD. (JP) 1985-05-07 US disclosed
US-4035512-A Aminotetralols TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559504-B2 Benzotriazole derivative KEAP1, NFE2L2, NCOR1 CA12 4658/4885CA1 4424/4885CA2 3070/4885
US-12011432-B2 Method of modulating ribonucleotide reductase RRM2, RRM2B, RRM1 CA12 2636/4885CA1 2716/4885CA2 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.