Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512324 | 0.85 | MEN1 (0.51) | NCEH1MEN1KMT2ANR4A2TAS1R3 | |
| SCHEMBL998157 | 0.85 | MEN1 (0.47) | NCEH1MEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL27862428 | 0.84 | TAS1R3 (0.46) | NCEH1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL14052524 | 0.83 | NCEH1 (0.54) | NCEH1MEN1KMT2ANR4A2TAS1R3 | |
| SCHEMBL277281 | 0.83 | KMT2A (0.57) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL1638703 | 0.82 | CA12 (0.60) | NCEH1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL71131 | 0.82 | NCEH1 (0.59) | NCEH1MEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL29404644 | 0.82 | NCEH1 (0.59) | NCEH1MEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL230034 | 0.81 | TSHR (0.54) | NCEH1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL29626829 | 0.81 | TSHR (0.54) | NCEH1MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580225-A | PRMT5-MTA synergistic inhibitor and application thereof | 甘李药业股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-11370882-B2 | Resin produced by polycondensation, and resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-06-28 | — | — | US | disclosed |
| US-20220146713-A1 | OPTICAL LENS | TEIJIN LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-10689486-B2 | Resin produced by polycondensation, and resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-20200190259-A1 | RESIN PRODUCED BY POLYCONDENSATION, AND RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-06-18 | — | — | US | disclosed |
| EP-3483197-A1 | RESIN PRODUCED BY POLYCONDENSATION, AND RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-3141570-B1 | RESIN PRODUCED BY POLYCONDENSATION, AND RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-12-05 | — | — | EP | disclosed |
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-3141570-A1 | RESIN PRODUCED BY POLYCONDENSATION, AND RESIN COMPOSITION | Mitsubishi Gas Chemical Company, Inc. (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-20170044312-A1 | RESIN PRODUCED BY POLYCONDENSATION, AND RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-02-16 | — | — | US | disclosed |
| US-20160051531-A1 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN INC (US) | 2016-02-25 | — | — | US | disclosed |
| US-9067905-B2 | Sulphone compounds and methods of making and using same | ZAFGEN, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20130053364-A1 | Sulphone Compounds and Methods of Making and Using Same | ZAFGEN, INC. | 2013-02-28 | — | — | US | disclosed |
| EP-2486004-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | Zafgen Corporation (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | NCEH1 5/4885MEN1 2847/4885KMT2A 404/4885 |
| US-20160051531-A1 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | METAP2, DNPEP, STS | NCEH1 230/4885MEN1 1603/4885KMT2A 666/4885 |
| US-20130053364-A1 | Sulphone Compounds and Methods of Making and Using Same | METAP2, DNPEP, STS | NCEH1 230/4885MEN1 1603/4885KMT2A 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.