Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709983 | 0.84 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL22395412 | 0.84 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL25303278 | 0.84 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL25389134 | 0.84 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL9278178 | 0.84 | THRB (0.59) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL7902919 | 0.83 | PTPN1 (0.38) | USP2CYP3A4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1164867 | 0.81 | THRB (0.62) | THRBUSP2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL13563298 | 0.80 | LMNA (0.38) | THRBLMNAALDH1A1 | |
| SCHEMBL11228724 | 0.78 | THRB (0.53) | THRBLMNAALDH1A1 | |
| SCHEMBL20916752 | 0.76 | FOLH1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028206-A2 | METHOD FOR PRODUCING REACTIVE MONOLAYER UNITS | Universität Linz (AT) | 2008-03-13 | — | — | WO | disclosed |