Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607569 | 0.87 | KCNH2 (0.50) | APPMAPTKCNH2NPC1RAB9A | |
| SCHEMBL17104750 | 0.80 | APP (0.58) | APPMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20593905 | 0.80 | GRM5 (0.52) | APPMAPTNPC1RAB9AGRM5 | |
| SCHEMBL10300049 | 0.80 | APP (0.63) | APPMAPTKCNH2NPC1RAB9A | |
| SCHEMBL3796509 | 0.79 | APP (0.80) | APPMAPTKCNH2NPC1RAB9A | |
| SCHEMBL22504232 | 0.79 | MAPT (0.54) | APPMAPTNPC1GRM5FFAR1 | |
| SCHEMBL10491818 | 0.78 | APP (0.43) | APPMAPTKCNH2NPC1RAB9A | |
| SCHEMBL952971 | 0.78 | APP (0.60) | APPMAPTKCNH2NPC1RAB9A | |
| SCHEMBL16796016 | 0.77 | AKR1C3 (0.44) | APPMAPTNPC1RAB9AFFAR1 | |
| SCHEMBL8424794 | 0.76 | APP (0.57) | APPMAPTNPC1RAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043299-B1 | Liquid crystalline compound, liquid crystal composition comprising the liquid crystalline compound, and liquid crystal display device using the liquid crystal composition | CHISSO CORP (JP) | 2008-10-15 | — | — | EP | disclosed |