Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576350 | 0.81 | MEN1 (0.46) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL5134940 | 0.77 | APP (0.57) | MAPTNPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL28801371 | 0.77 | FFAR1 (0.45) | NPC1RAB9AFFAR1FFAR4CES2 | |
| SCHEMBL333008 | 0.75 | AKR1C3 (0.61) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL29433447 | 0.75 | AKR1C3 (0.61) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL5155932 | 0.75 | AKR1C3 (0.62) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL29855934 | 0.75 | NPC1 (0.66) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL4444737 | 0.75 | NPC1 (0.66) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL6839761 | 0.75 | MAPK14 (0.46) | MAPTRAB9AFFAR1FFAR4ALDH1A1 | |
| SCHEMBL7868906 | 0.75 | NPC1 (0.49) | AKR1C3MAPTNPC1RAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080189-B1 | POLYMERIC MATERIALS | VICTREX MFG LTD (GB) | 2020-02-12 | — | — | EP | disclosed |
| US-20160304667-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| EP-3080189-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015087059-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2015-06-18 | — | — | WO | disclosed |