Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 17/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072244 | 0.90 | CXCR3 (0.40) | CXCR3 | |
| SCHEMBL5136865 | 0.90 | TSHR (0.35) | CXCR3C5AR1 | |
| SCHEMBL5136555 | 0.89 | CXCR3 (0.33) | CXCR3C5AR1 | |
| SCHEMBL5135377 | 0.89 | CXCR3 (0.38) | CXCR3 | |
| SCHEMBL4763850 | 0.88 | TSHR (0.35) | CXCR3C5AR1 | |
| SCHEMBL5136862 | 0.87 | C5AR1 (0.36) | CXCR3C5AR1 | |
| SCHEMBL5136034 | 0.86 | CXCR3 (0.36) | CXCR3 | |
| SCHEMBL5136913 | 0.84 | ABCC1 (0.38) | CXCR3C5AR1 | |
| SCHEMBL5135283 | 0.84 | NPC1 (0.36) | CXCR3 | |
| SCHEMBL1912805 | 0.83 | PTGES (0.37) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490044-A4 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORP (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1490044-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084524-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |