SCHEMBL5135053

SCHEMBL5135053

C=CCOC(=O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.49
CYP3A4 P08684 2/20 0.49
KDM4E B2RXH2 4/20 0.47
HTT P42858 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
FFAR1 O14842 1/20 0.41
CSNK2A2 P19784 1/20 0.41
CSNK2A1 P68400 1/20 0.41
NPC1 O15118 2/20 0.40
RHOA P61586 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HSP90AA1 P07900 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9278114 0.98 SNCA (0.48) SNCACYP3A4KDM4EHTTALDH1A1
SCHEMBL28138625 0.95 SNCA (0.48) SNCACYP3A4KDM4EHTTALDH1A1
SCHEMBL30107706 0.93 CYP3A4 (0.55) SNCACYP3A4KDM4EALDH1A1HSD17B10
SCHEMBL429872 0.93 CYP3A4 (0.55) SNCACYP3A4KDM4EALDH1A1HSD17B10
SCHEMBL17386426 0.88 CYP3A4 (0.53) SNCACYP3A4KDM4EALDH1A1HSD17B10
SCHEMBL28870175 0.88 CYP3A4 (0.69) SNCACYP3A4KDM4EHTTALDH1A1
SCHEMBL4430256 0.87 CYP3A4 (0.57) SNCACYP3A4KDM4EHTTALDH1A1
SCHEMBL18593579 0.86 CA12 (0.53) SNCACYP3A4KDM4EALDH1A1NPC1
SCHEMBL4907430 0.86 SNCA (0.48) SNCACYP3A4KDM4EALDH1A1HSD17B10
SCHEMBL9278105 0.86 SNCA (0.48) SNCACYP3A4KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7355071-B2 Method for preparing 2,6-naphthalene dicarboxylic acid KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2008-04-08 US claimed
EP-1591435-A2 Method for preparing 2,6-Naphtalene dicarboxyclic acid KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2005-11-02 EP claimed
US-20050240056-A1 Method for preparing 2,6-naphthalene dicarboxylic acid KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2005-10-27 US claimed
JP-8283395-A None JP disclosed
JP-4359048-A None JP disclosed
JP-7242741-A None JP disclosed
CN-114667443-A Optical detection module with adjustable sensitivity 贝克顿·迪金森公司 2022-06-24 CN disclosed
CN-113574361-A System for sorting cells based on frequency encoded images and methods of use thereof 贝克顿·迪金森公司 2021-10-29 CN disclosed
CN-113508286-A Light detection system and method of use 贝克顿·迪金森公司 2021-10-15 CN disclosed
CN-113302470-A Droplet sorting decision module, system and method of use thereof 贝克顿·迪金森公司 2021-08-24 CN disclosed
CN-112805548-A Particle sorting module with alignment window, system and method of use thereof 贝克顿·迪金森公司 2021-05-14 CN disclosed
WO-1997029091-A1 BALANOL ANALOGUES PHYTERA SYMBION APS (DK) 1997-08-14 WO disclosed
JP-H08283395-A PRODUCTION OF POLYETHYLENE 2,6-NAPHTHALATE FUJI PHOTO FILM CO LTD 1996-10-29 JP disclosed
JP-H07242741-A PRODUCTION OF POLYESTER DIAFOIL CO LTD 1995-09-19 JP disclosed
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
JP-H04359048-A POLYESTER COMPOSITION DIAFOIL CO LTD 1992-12-11 JP disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed
US-3937689-A ALLYL ESTERS OF BENZENE AND NAPHTHALENE DICARBOXYLIC ACIDS TEIJIN LTD. (JA) 1976-02-10 US disclosed