Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429872 | 0.93 | CYP3A4 (0.55) | CYP3A4ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL30107706 | 0.93 | CYP3A4 (0.55) | CYP3A4ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL17386426 | 0.92 | CYP3A4 (0.53) | CYP3A4ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5135053 | 0.87 | SNCA (0.49) | CYP3A4ALDH1A1KDM4EMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9278114 | 0.86 | SNCA (0.48) | CYP3A4ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL9278105 | 0.86 | SNCA (0.48) | CYP3A4ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL18593579 | 0.86 | CA12 (0.53) | CYP3A4ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4907430 | 0.86 | SNCA (0.48) | CYP3A4ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL11046516 | 0.86 | PTPN11 (0.54) | CYP3A4ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL28138625 | 0.86 | SNCA (0.48) | CYP3A4ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791824-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | Showa Denko K.K. (JP) | 2007-06-06 | — | — | EP | claimed |
| WO-2006033438-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | SHOWA DENKO K.K. (JP) | 2006-03-30 | — | — | WO | claimed |
| EP-1328560-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | Showa Denko K.K. (JP) | 2003-07-23 | — | — | EP | claimed |
| WO-2002026843-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-04-04 | — | — | WO | claimed |
| EP-2094654-A1 | RADICALLY POLYMERIZABLE COMPOUND HAVING A DITHIOCARBONATE STRUCTURE AND A SULFUR-CONTAINING ALLYLCARBONATE | Showa Denko K.K. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008062903-A1 | RADICALLY POLYMERIZABLE COMPOUND HAVING A DITHIOCARBONATE STRUCTURE AND A SULFUR-CONTAINING ALLYLCARBONATE | SHOWA DENKO K.K. (JP) | 2008-05-29 | — | — | WO | disclosed |
| EP-1791824-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | Showa Denko K.K. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033438-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | SHOWA DENKO K.K. (JP) | 2006-03-30 | — | — | WO | disclosed |
| US-6846900-B2 | POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K.K. (JP) | 2005-01-25 | — | — | US | disclosed |
| US-20030208019-A1 | Plastic lens composition, plastic lens, and process for producing the plastic lens | SHOWA DENKO K.K. (JP) | 2003-11-06 | — | — | US | disclosed |
| US-20030144447-A1 | Novel polyvalent carboxylic acid ester and their use in plastic lens compositions | SHOW A DENKO K.K. (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1328560-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | Showa Denko K.K. (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002079140-A1 | NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS | SHOWA DENKO K. K. (JP) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002072651-A1 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002026843-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144447-A1 | Novel polyvalent carboxylic acid ester and their use in plastic lens compositions | VCL, VIM, CRYAA | CYP3A4 1715/4885ALDH1A1 1516/4885KDM4E 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.