Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497264 | 0.90 | HPGD (0.56) | KMT2AGAAPKMSMN1; SMN2HPGD | |
| SCHEMBL27967057 | 0.85 | TAAR1 (0.61) | KMT2AGAAPKMHPGDKCNK3 | |
| SCHEMBL9547528 | 0.82 | KMT2A (0.61) | KMT2AGAAPKMSMN1; SMN2HPGD | |
| SCHEMBL28251299 | 0.81 | HPGD (0.51) | KMT2APKMSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL27967054 | 0.80 | TAAR1 (0.54) | PKMHPGDKCNK3CSF1RBRAF | |
| SCHEMBL3429605 | 0.79 | NPC1 (0.56) | KMT2AGAAPKMSMN1; SMN2HPGD | |
| SCHEMBL28027180 | 0.79 | HPGD (0.49) | KMT2APKMSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL27916737 | 0.77 | TAAR1 (0.61) | KMT2APKMCSF1RMEN1BRAF | |
| SCHEMBL9192069 | 0.76 | KMT2A (0.72) | KMT2AGAAPKMSMN1; SMN2IMPDH2 | |
| Hydrochloric Acid SCHEMBL9187992 | 0.75 | KMT2A (0.70) | KMT2AGAAPKMSMN1; SMN2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648905-B1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | claimed |