Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251299 | 0.86 | HPGD (0.51) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL16518668 | 0.82 | HSD17B10 (0.57) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL2497264 | 0.82 | HPGD (0.56) | KMT2AMEN1HSP90AA1HPGDPKM | |
| SCHEMBL5135347 | 0.82 | KMT2A (0.50) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL28027180 | 0.81 | HPGD (0.49) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL8153658 | 0.81 | HSD17B10 (0.65) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL7618599 | 0.79 | HSD17B10 (0.62) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL10212285 | 0.78 | KDR (0.57) | KMT2AMEN1HSP90AA1HSD17B10HPGD | |
| SCHEMBL5545056 | 0.77 | HSD17B10 (0.69) | KMT2AMEN1HSD17B10HPGDRXFP1 | |
| SCHEMBL8094338 | 0.77 | HSD17B10 (0.64) | KMT2AMEN1HSP90AA1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194660-A | Processes for producing carbamates and isocyanates | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0083096-B1 | PRODUCTION OF URETHANE COMPOUNDS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-02-25 | — | — | EP | disclosed |
| US-4621149-A | PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |