Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135613 | 0.81 | SCN9A (0.35) | MAPTLMNAL3MBTL1POLBPKM | |
| SCHEMBL810145 | 0.81 | PIM1 (0.39) | MAPTLMNAL3MBTL1POLBPKM | |
| SCHEMBL811189 | 0.76 | PIM1 (0.42) | MAPTLMNAPOLBHPGDALDH1A1 | |
| SCHEMBL810905 | 0.75 | PIM1 (0.42) | MAPTLMNAPOLBHPGDALDH1A1 | |
| SCHEMBL811281 | 0.73 | PIM1 (0.43) | MAPTPOLBPKMHPGDALDH1A1 | |
| SCHEMBL810498 | 0.71 | PIM1 (0.41) | MAPTLMNARXFP1SCN9ATP53 | |
| SCHEMBL810146 | 0.70 | METAP2 (0.40) | MAPTLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL811196 | 0.69 | PIM1 (0.45) | MAPTLMNAL3MBTL1POLBHPGD | |
| SCHEMBL810346 | 0.67 | MAPT (0.40) | MAPTLMNAL3MBTL1HPGDALDH1A1 | |
| SCHEMBL811090 | 0.67 | LMNA (0.39) | MAPTLMNAMAPK1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |