Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135834 | 0.93 | THRA (0.31) | — | |
| SCHEMBL3127197 | 0.87 | THRA (0.35) | NTRK1NTRK2 | |
| SCHEMBL3136098 | 0.86 | ACSS2 (0.35) | — | |
| SCHEMBL3128023 | 0.86 | ACSS2 (0.35) | — | |
| SCHEMBL5137904 | 0.74 | ACSS2 (0.33) | — | |
| SCHEMBL3142258 | 0.74 | THRA (0.36) | — | |
| SCHEMBL3130577 | 0.73 | ACSS2 (0.40) | — | |
| SCHEMBL3133600 | 0.73 | ACSS2 (0.40) | — | |
| SCHEMBL3137672 | 0.73 | RAF1 (0.37) | — | |
| SCHEMBL3142133 | 0.69 | POLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899309-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003419-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2007-01-11 | — | — | WO | disclosed |