Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281747 | 0.92 | — | — | |
| SCHEMBL10522037 | 0.90 | TSHR (0.44) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL9440527 | 0.90 | — | — | |
| SCHEMBL10868404 | 0.90 | — | — | |
| SCHEMBL8680595 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL5886689 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL29150311 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL6744017 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL29170278 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL4433196 | 0.88 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846098-B2 | IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES | UNION CARBIDE CHEM PLASTIC (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-0846098-B1 | IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES | UNION CARBIDE CHEM PLASTIC (US) | 2003-03-26 | — | — | EP | disclosed |