Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5136085 | 0.90 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL5135509 | 0.90 | TSHR (0.38) | — | |
| SCHEMBL5135873 | 0.88 | TSHR (0.35) | AGTR1 | |
| SCHEMBL5134636 | 0.88 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL5135023 | 0.84 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL5135175 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL14415666 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL4770835 | 0.83 | TSHR (0.39) | — | |
| SCHEMBL5137587 | 0.83 | PDK1 (0.36) | — | |
| SCHEMBL5136526 | 0.82 | C5AR1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490044-A4 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORP (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1490044-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084524-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |