Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073394 | 0.86 | CYP24A1 (0.33) | CYP2C19ALDH1A1CYP3A4CYP24A1 | |
| SCHEMBL18002093 | 0.84 | SLC6A4 (0.39) | CYP2C19CYP3A4CYP24A1HSD11B1KMT2A | |
| SCHEMBL6620603 | 0.75 | HTT (0.36) | CYP2C19ALDH1A1CYP3A4CYP24A1KMT2A | |
| SCHEMBL7984628 | 0.75 | IDO1 (0.40) | ALDH1A1CYP3A4CYP24A1KMT2ACYP2C9 | |
| SCHEMBL991557 | 0.72 | TSHR (0.33) | ALDH1A1CYP24A1TSHR | |
| SCHEMBL8126233 | 0.71 | LMNA (0.41) | CYP2C19ALDH1A1CYP3A4CYP24A1KMT2A | |
| SCHEMBL27813441 | 0.69 | MAOA (0.39) | ALDH1A1CYP3A4TSHRCYP2D6 | |
| SCHEMBL1790143 | 0.68 | TSHR (0.36) | CYP2C19ALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL3369244 | 0.66 | CYP3A4 (0.61) | CYP2C19ALDH1A1CYP3A4HSD11B1KMT2A | |
| SCHEMBL21529608 | 0.66 | PDE2A (0.38) | CYP2C19ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986649-A2 | NOVEL POLYMORPHS OF MONTELUKAST AMMONIUM SALTS AND PROCESSES FOR PREPARATION THEREFOR | CHEMAGIS LTD. (IL) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007096875-A2 | NOVEL POLYMORPHS OF MONTELUKAST AMMONIUM SALTS AND PROCESSES FOR PREPARATION THEREFOR | CHEMAGIS LTD. (IL) | 2007-08-30 | — | — | WO | disclosed |