Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibutylsuccinate SCHEMBL27564311 | 0.98 | DGKA (0.61) | DGKAAKR1B1GPR84PPARGPPARD | |
| Dibutylsuccinate SCHEMBL7758479 | 0.96 | DGKA (0.59) | DGKAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL459010 | 0.96 | DGKA (0.57) | DGKAAKR1B1GPR84PPARGPPARD | |
| Dibutylsuccinate SCHEMBL28147008 | 0.96 | DGKA (0.57) | DGKAAKR1B1GPR84PPARGPPARD | |
| Adipic Acid SCHEMBL5485576 | 0.94 | DGKA (0.67) | DGKAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL365683 | 0.94 | DGKA (0.67) | DGKAAKR1B1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL27572777 | 0.94 | DGKA (0.67) | DGKAAKR1B1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL9414457 | 0.94 | DGKA (0.55) | DGKAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL405153 | 0.92 | DGKA (0.70) | DGKAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL3447290 | 0.92 | DGKA (0.70) | DGKAAKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158990-A1 | BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE | PROCTER & GAMBLE (US) | 2024-05-16 | — | — | US | claimed |
| US-11913173-B2 | Biodegradable and recyclable barrier paper laminate | THE PROCTER & GAMBLE COMPANY (US) | 2024-02-27 | — | — | US | claimed |
| EP-4225663-A1 | BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE | The Procter & Gamble Company (US) | 2023-08-16 | — | — | EP | claimed |
| US-20230250227-A1 | THERMOPLASTIC POLYESTER FOR PRODUCING 3D-PRINTED OBJECTS | ROQUETTE FRERES (FR) | 2023-08-10 | — | — | US | claimed |
| CN-116157268-A | Biodegradable and recyclable barrier paper laminate | 宝洁公司 | 2023-05-23 | — | — | CN | claimed |
| WO-2022077008-A1 | BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE | THE PROCTER & GAMBLE COMPANY (US) | 2022-04-14 | — | — | WO | claimed |
| EP-4370593-A1 | METHOD TO DEGRADE PLASTIC | Repsol, S.A. (ES) | 2024-05-22 | — | — | EP | disclosed |
| US-20230250227-A1 | THERMOPLASTIC POLYESTER FOR PRODUCING 3D-PRINTED OBJECTS | ROQUETTE FRERES (FR) | 2023-08-10 | — | — | US | disclosed |
| WO-2023285648-A1 | METHOD TO DEGRADE PLASTIC | REPSOL, S.A. (ES) | 2023-01-19 | — | — | WO | disclosed |
| US-7388058-B2 | Polyester blend compositions and biodegradable films produced therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| EP-1504059-B1 | POLYESTER BLEND COMPOSITIONS AND BIODEGRADABLE FILMS PRODUCED THEREFROM | DU PONT (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1504059-A1 | POLYESTER BLEND COMPOSITIONS AND BIODEGRADABLE FILMS PRODUCED THEREFROM | E. I. du Pont de Nemours and Company (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20030220456-A1 | Polyester blend compositions and biodegradable films produced therefrom | DUPONT INDUSTRIAL BIOSCIENCES USA, LLC | 2003-11-27 | — | — | US | disclosed |
| WO-2003095555-A1 | POLYESTER BLEND COMPOSITIONS AND BIODEGRADABLE FILMS PRODUCED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-20 | — | — | WO | disclosed |