SCHEMBL51376

SCHEMBL51376

COC(=O)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28292409 0.97
SCHEMBL27817139 0.91 ALDH1A1 (0.46)
SCHEMBL11145544 0.79 ALDH1A1 (0.45)
SCHEMBL9720619 0.79 ALDH1A1 (0.45)
SCHEMBL1578778 0.79
SCHEMBL9720623 0.79 ALDH1A1 (0.45)
SCHEMBL6950834 0.76 ALDH1A1 (0.56)
SCHEMBL8295 0.76
SCHEMBL8402377 0.76
SCHEMBL11854578 0.76 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4393 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459883-B2 Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof Kynan Duke IP, LLC (US) 2025-11-04 US claimed
US-12404284-B2 Spirocyclic inhibitors of hepatitis B virus OSPEDALE SAN RAFFAELE S.R.L. (IT) 2025-09-02 US claimed
WO-2025137231-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2025-06-26 WO claimed
CN-119409710-A Oxamide substituted hepatitis b virus tricyclic inhibitors 圣拉斐尔医院有限公司 2025-02-11 CN claimed
EP-4494709-A2 SPIROCYCLIC INHIBITORS OF HEPATITIS B VIRUS Ospedale San Raffaele S.r.l. (IT) 2025-01-22 EP claimed
CN-114555608-B Oxamide substituted hepatitis b virus tricyclic inhibitors 圣拉斐尔医院有限公司 2024-11-01 CN claimed
EP-4103567-B1 SPIROCYCLIC INHIBITORS OF HEPATITIS B VIRUS OSPEDALE SAN RAFFAELE SRL (IT) 2024-10-23 EP claimed
US-12060363-B2 Isohexide-dioxalate compound, its polymers and application thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-08-13 US claimed
CN-118290458-A Preparation method and application of biocompatible BODIPY-based near-infrared photosensitizer 南开大学 2024-07-05 CN claimed
CN-118290459-A Preparation and application of spiral photosensitizer for directionally inducing cell apoptosis 南开大学 2024-07-05 CN claimed
EP-1487450-A1 PROCESS FOR THE PREPARATION OF ANTIVIRAL 7-AZAINDOLE DERIVATIVES Bristol-Myers Squibb Company (US) 2004-12-22 EP claimed
CN-1542001-A Small molecule inhibitors of rotamase enzyme activity GPI����عɹ�˾ 2004-11-03 CN claimed
EP-0992492-B1 Small molecule inhibitors of rotamase enzyme activity GUILFORD PHARM INC (US) 2004-08-25 EP claimed
EP-1433781-A1 Pyrrolidine carboxylic acid derivatives GPI NIL Holdings, Inc. (US) 2004-06-30 EP claimed
US-20040044025-A1 Processes for the preparation of antiviral 7-azaindole derivatives BRISTOL-MYERS SQUIBB COMPANY 2004-03-04 US claimed
WO-2003082289-A1 PROCESS FOR THE PREPARATION OF ANTIVIRAL 7-AZAINDOLE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-10-09 WO claimed
EP-0992492-A1 Small molecule inhibitors of rotamase enzyme activity GUILFORD PHARMACEUTICALS INC. (US) 2000-04-12 EP claimed
CN-1127757-A Novel tetrahydropyran compounds, their preparation and pharmaceutical compositions containing them ADIR (FR) 1996-07-31 CN claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
US-4620010-A Process for preparing carboalkoxy substituted benzoxazole compounds USV PHARMACEUTICAL CORP. (US) 1986-10-28 US claimed