SCHEMBL9720623

SCHEMBL9720623

COC(=O)C(Cl)=C(Cl)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TET2 Q6N021 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
TSHR P16473 4/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
HSD17B10 Q99714 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
MAPT P10636 1/20 0.31
TGFBR1 P36897 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720619 1.00 ALDH1A1 (0.45) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL11145544 1.00 ALDH1A1 (0.45) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL11354025 0.88 ALDH1A1 (0.38) ALDH1A1TET2EGLN1TGFBR1
SCHEMBL11354020 0.88 ALDH1A1 (0.38) ALDH1A1TET2EGLN1TGFBR1
SCHEMBL9597506 0.87
SCHEMBL8571994 0.84
SCHEMBL11593610 0.84 ALDH1A1 (0.39) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL20924920 0.82 ALDH1A1 (0.38) ALDH1A1TET2EGLN1TGFBR1
SCHEMBL11147128 0.82 ALDH1A1 (0.43) ALDH1A1TET2EGLN1MGAMGAA
SCHEMBL8970856 0.82 ALDH1A1 (0.43) ALDH1A1TET2EGLN1MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed
US-5101067-A Chemical intermediates for pyridinedicarboxylic acid esters, herbicides WACKER-CHEMIE GMBH (DE) 1992-03-31 US disclosed
US-5008392-A Reacting 2,3-dihalomaleic acid esters with ammonia or salts, reacting product with alpha, B-unsaturated aldehydes or ketones WACKER-CHEMIE GMBH (DE) 1991-04-16 US disclosed
US-4582849-A Fungicidal N-substituted maleic acid imides BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US disclosed
US-4383053-A Antifouling paints having fumaric acid ester polymer NIPPON OIL AND FATS CO., LTD. (JP) 1983-05-10 US disclosed
US-4010182-A Method for producing N-(4-fluorophenyl)-2,3,-dichloromaleimide MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-03-01 US disclosed