SCHEMBL5137670

SCHEMBL5137670

CCCCC(C)(C=O)CCC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
FDPS P14324 1/20 0.32
ADH1B P00325 3/20 0.32
ADH1C P00326 3/20 0.32
ADH1A P07327 3/20 0.32
ADH7 P40394 3/20 0.32
ADH4 P08319 2/20 0.31
EPHX1 P07099 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
FAAH O00519 2/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9171978 0.95 TSHR (0.39) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL28358059 0.93 TSHR (0.37) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL10304506 0.93 TSHR (0.37) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL9245830 0.90 TSHR (0.39) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL5682325 0.89 ALDH1A1 (0.33) TSHRFDPSALDH1A1
SCHEMBL8955012 0.86 FDPS (0.34) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL9220588 0.85 TSHR (0.44) TSHRFDPSADH1BADH1CADH1A
SCHEMBL276807 0.85 TSHR (0.36) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL9578451 0.79 FDPS (0.38) FDPS
SCHEMBL2009418 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008084046-A1 PLASTICIZERS FOR POLYVINYL ACETALS AND POLYSULFIDES BASF SE (DE) 2008-07-17 WO disclosed
EP-0381040-B1 METHOD FOR THE PREPARATION OF 2,2-DIALKYLPROPIONALDEHYDES BASF Aktiengesellschaft (DE) 1993-03-31 EP disclosed
US-5012006-A Hydroformylation of 1,1-dialkylethylenes in presence of cobalt carbonyl complex catalysts, water-containing solvents or lactones or sulfones BASF AKTIENGESELLSCHAFT (DE) 1991-04-30 US disclosed
EP-0381040-A2 Method for the preparation of 2,2-dialkylpropionaldehydes BASF Aktiengesellschaft (DE) 1990-08-08 EP disclosed