Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | SCN1A | P35498 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181901 | 0.94 | ALDH1A1 (0.69) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL22773392 | 0.94 | ALDH1A1 (0.69) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL29204388 | 0.90 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL7734044 | 0.89 | TSHR (0.65) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL11109738 | 0.88 | ALDH1A1 (0.68) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL7530338 | 0.88 | ALDH1A1 (0.68) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL7159501 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL9363450 | 0.86 | TSHR (0.60) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL28326757 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL11506341 | 0.85 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1933841-A1 | COMBINATION THERAPY COMPRISING SUBSTITUTED OXAZOLIDINONES FOR THE PREVENTION AND TREATMENT OF CEREBRAL CIRCULATORY DISORDERS | Bayer HealthCare AG (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007039134-A1 | COMBINATION THERAPY COMPRISING SUBSTITUTED OXAZOLIDINONES FOR THE PREVENTION AND TREATMENT OF CEREBRAL CIRCULATORY DISORDERS | BAYER HEALTHCARE AG (DE) | 2007-04-12 | — | — | WO | disclosed |